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Anti-Hepatitis A virus Polyprotein VP1 Polyclonal Antibody

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Cat.No：K009675P-Biotin Solarbio

Storage：Store at -20℃. Avoid freeze / thaw cycles.

Host：Rabbit

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Background	Capsid proteins VP1, VP2, and VP3 form a closed capsid enclosing the viral positive strand RNA genome. All these proteins contain a beta-sheet structure called beta-barrel jelly roll. Together they form an icosahedral capsid (T=3) composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximately 300 Angstroms. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes. The capsid interacts with HAVCR1 to provide virion attachment to target cell. VP0 precursor is a component of immature procapsids. The N-terminal domain of VP0, protein VP4, is needed for the assembly of 12 pentamers into the icosahedral structure. Unlike other picornaviruses, HAV VP4 does not seem to be myristoylated and has not been detected in mature virions, supposedly owing to its small size. VP1-2A precursor is a component of immature procapsids and corresponds to an extended form of the structural protein VP1. The C-terminal domain of VP1-2A, protein 2A, acts as an assembly signal t
Subtype	IgG
Storage	Store at -20℃. Avoid freeze / thaw cycles.
Host	Rabbit
Application	WB ELISA IHC ICC IF
Dilution Ratio	WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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