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My CartReactivity：Human
Application：Cy5
Clone Type：Monoclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：2067
Host：Mouse
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| Reactivity | Human |
| Background | The product of this gene functions in the nucleotide excision repair pathway,and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin.The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4),and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion.The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks.Mutations in this gene result in cerebrooculofacioskeletal syndrome,and polymorphisms that alter expression of this gene may play a role in carcinogenesis.Multiple transcript variants encoding different isoforms have been found for this gene.The last exon of this gene overlaps with the CD3e molecule,epsilon associated protein gene on the opposite strand.[provided by RefSeq,Oct 2009] |
| Subtype | IgG2b |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Host | Mouse |
| Application | WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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