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My Cart> Antibodies > Primary Antibodies > Anti-Caspase-1 P10 Polyclonal AntibodyBiotinReactivity：Mouse,Human
Application：Biotin
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：834
Host：Rabbit
Qty：
Size：
| Reactivity | Mouse,Human |
| Background | Thiol protease involved in a variety of inflammatory processes by proteolytically cleaving other proteins， such as the precursors of the inflammatory cytokines interleukin-1 beta (IL1B) and interleukin 18 (IL18) as well as the pyroptosis inducer Gasdermin-D (GSDMD)， into active mature peptides (PubMed:15326478， PubMed:15498465， PubMed:1574116， PubMed:26375003， PubMed:32051255， PubMed:37993714， PubMed:7876192， PubMed:9334240). Plays a key role in cell immunity as an inflammatory response initiator: once activated through formation of an inflammasome complex， it initiates a pro-inflammatory response through the cleavage of the two inflammatory cytokines IL1B and IL18， releasing the mature cytokines which are involved in a variety of inflammatory processes (PubMed:15326478， PubMed:15498465， PubMed:1574116， PubMed:32051255， PubMed:7876192). |
| Subtype | IgG |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Host | Rabbit |
| Application | WB ELISA IHC ICC IF |
| Dilution Ratio | WB 1:50-200. ELISA 1:100-1000. IHC 1:20-200. ICC 1:50-200. IF 1:50-200 |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Note：
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