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My Cart> Antibodies > Primary Antibodies > Anti-PSMC4 Polyclonal AntibodySAlexa Fluor 405Reactivity：Mouse,Rat,Human;Mouse;Rat,Human
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Host：Rabbit
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| Reactivity | Mouse,Rat,Human;Mouse;Rat,Human |
| Background | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes，a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits;2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base，which contains 6 ATPase subunits and 2 non-ATPase subunits，and a lid，which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin，a liver oncoprotein，and may also play a role in Parkinson’s disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observe |
| Subtype | IgG |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Host | Rabbit |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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