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My Cart> Antibodies > Primary Antibodies > Anti-TGFB1 Polyclonal AntibodySAlexa Fluor 680Reactivity：Human,Human;Mouse;Rat,Rat,Mouse
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Host：Rabbit
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| Reactivity | Human,Human;Mouse;Rat,Rat,Mouse |
| Background | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide，and is found in either a latent form composed of a mature peptide homodimer，a LAP homodimer，and a latent TGF-beta binding protein，or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation，differentiation and growth，and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells，and mutations in this gene result in Camurati-Engelmann disease. |
| Subtype | IgG |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Host | Rabbit |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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