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My CartReactivity：Mouse,Human
Application：FCM,WB
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：834
Host：Rabbit
Qty：
Size：
| Name | Anti-Caspase-1 P10 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:500-2000. FCM 1ug/Test. |
| Target | Caspase-1 P10 |
| Background | Thiol protease involved in a variety of inflammatory processes by proteolytically cleaving other proteins， such as the precursors of the inflammatory cytokines interleukin-1 beta (IL1B) and interleukin 18 (IL18) as well as the pyroptosis inducer Gasdermin-D (GSDMD)， into active mature peptides (PubMed:15326478， PubMed:15498465， PubMed:1574116， PubMed:26375003， PubMed:32051255， PubMed:37993714， PubMed:7876192， PubMed:9334240). Plays a key role in cell immunity as an inflammatory response initiator: once activated through formation of an inflammasome complex， it initiates a pro-inflammatory response through the cleavage of the two inflammatory cytokines IL1B and IL18， releasing the mature cytokines which are involved in a variety of inflammatory processes (PubMed:15326478， PubMed:15498465， PubMed:1574116， PubMed:32051255， PubMed:7876192). |
| Swiss Prot | P29466 |
| Gene ID | 834 |
| Subcellular Location | Cytoplasm |
| Immunogen | A synthetic peptide of human Caspase-1 P10 |
| Public Immunogen Range | 321-404aa |
| Calculated MW | 10/30/35/43/45kDa |
| Observed MW | 45kDa |
| Purification Method | Affinity purification |
| Storage Buffer | 0.01M TBS (pH7.4) with 1% BSA， 0.02% Proclin300 and 50% Glycerol. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | 支 |
| Specification | 50ul 100ul |
| Reactivity | Human Mouse |
| Application | WB FCM |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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