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Kisspeptin-10,human

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Cat.No：CLP1111 Solarbio

CAS：374675-21-5

Purity：≥95%

Appearance：Lyophilized powder

Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)

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Product Information

Product Type	Peptides
CAS	374675-21-5
Sequence(1LC)	YNWNSFGLRF-NH2
Sequence(3LC)	Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Molecular Formula	C63H83N17O14
Molecular Weight	1302.46
Purity	≥95%
Appearance	Lyophilized powder
Solubility	DMSO：100 mg/mL; H2O：4 mg/mL; *Ultrasonic solubilization;
Salt Form	Trifluoroacetate salt
Source	Synthetic
Storage	Store at -20℃，2 years.(Avoid freeze/thaw cycles)
Category/Label	Substrate and Enzyme Inhibitors
Background	Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression.
In Vitro	Kisspeptin-10 (KP-10) and its receptor GPR54 are key components in the regulation of GnRH secretion in humans and other mammals. Kisspeptin-10 protein binds to GPR54. Activation of Kisspeptin-10 suppresses pulmonary human melanoma and Kisspeptin-10 is a metastasis suppressor in breast cancer cells.
Reference	[1] Kadokawa, H. et al. J. Endocrinol. 196, 331 (2008); [2] Kotani, M. et al. J. Biol. Chem. 276, 34631 (2001); [3] Navenot, J.M. et al. Cancer Res, 65, 10450 (2005).
Unit	Bottle
Specification	1mg 5mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.