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My Cart> Peptides > Neuropeptides & Related Peptides > Myelin Oligodendrocyte Glycoprotein Peptide (35-55), (mouse,rat)CAS：149635-73-4
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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| Product Type | Peptides |
| CAS | 149635-73-4 |
| Sequence(1LC) | MEVGWYRSPFSRVVHLYRNGK |
| Sequence(3LC) | Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys |
| Molecular Formula | C118H177N35O29S1 |
| Molecular Weight | 2581.98 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Solubility | H2O：≥50 mg/mL; *Ultrasonic solubilization; |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Neuropeptides and Related Peptides |
| Background | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat produces a relapsing-remitting neurological disease with extensive plaque-like demyelination. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat induces strong T and B cell responses and is highly encephalitogenic. |
| In Vitro | Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55); 0-50 μg/mL; 72 h; lymph nodes cells) induces T cell proliferative and secretes Th1 cytokines including IFN-γ, TNF-α, IL-10, IL-4 and IL-5. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat increases the level of IgG. |
| In Vivo | Myelin oligodendrocyte glycoprotein (MOG) peptide 35-55 is one target of the autoreactive T cell response, leading to an acute and later chronic autoimmune process. MOG 35-55 is able to induce experimental autoimmune encephalomyelitis (EAE) in the B6 mouse. |
| Reference | [1] Slavin, A. et al. Autoimmunity 28, 109 (1998); [2] Ichikawa, M. et al. Cellular Immunol 19[1] 97 (1999); [3] Kennel De March, A. et al. J Neuroimmunol 135, 117 (2003); [4] Robinson, W. et al. Nat Biotech 21, 1033 (2003). |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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