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My Cart> Peptides > Other Peptides > Myelin Oligodendrocyte Glycoprotein Peptide (35-55), amide (mouse,rat)CAS：2022956-48-3
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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| Product Type | Peptides |
| CAS | 2022956-48-3 |
| Sequence(1LC) | MEVGWYRSPFSRVVHLYRNGK-NH2 |
| Sequence(3LC) | Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-NH2 |
| Molecular Formula | C118H178N36O28S1 |
| Molecular Weight | 2581 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Solubility | H2O：≥100 mg/mL; *Ultrasonic solubilization; |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Other Peptides |
| Background | MOG peptide (35-55) is highly encephalitogenic and can induce strong T and B cell responses. A single injection of this peptide produces a relapsing-remitting neurologic disease with extensive plaque-like demyelination. Because of the clinical, histopathologic, and immunologic similarities with multiple sclerosis (MS), this MOG-induced demyelinating encephalomyelitis may serve as a model for investigating MS. |
| In Vitro | The expanded CD4+ T?cells are largely specific for the myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide 35-55 (MOG35-55), while clonally expanded CD8+ T?cells were non-responsive to myelin peptides or proteins. |
| In Vivo | MOG(35-55) amide, mouse, rat (3 mg/mL for 0.1 mL; s.c.; single dose) results active induction of experimental autoimmune encephalomyelitis (EAE) in mice. MOG(35-55) amide, mouse, rat (200 μg; s.c.; single dose) induces a increasing concentration of the eosinophil chemoattractant eotaxin-1 in the spinal cord in the course of EAE induced in C57BL/6 mice. |
| Reference | [1] F.Puentes et al., J. Neuroinflammation, 10, 118(2013). |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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