IKVAV
Cat.No:CLP0652 Solarbio
CAS:131167-89-0
Molecular Formula:C25H48N6O6
Molecular Weight:528.69
Purity:≥95%
Appearance:Lyophilized powder
Storage:Store at -20℃,2 years.(Avoid freeze/thaw cycles)
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My CartCAS:131167-89-0
Molecular Formula:C25H48N6O6
Molecular Weight:528.69
Purity:≥95%
Appearance:Lyophilized powder
Storage:Store at -20℃,2 years.(Avoid freeze/thaw cycles)
Qty:
Size:
Product Type | Peptides |
CAS | 131167-89-0 |
Sequence(1LC) | IKVAV |
Sequence(3LC) | Ile-Lys-Val-Ala-Val |
Molecular Formula | C25H48N6O6 |
Molecular Weight | 528.69 |
Purity | ≥95% |
Appearance | Lyophilized powder |
Solubility | H2O:100 mg/mL; *Ultrasonic solubilization; |
Salt Form | Trifluoroacetate salt |
Source | Synthetic |
Storage | Store at -20℃,2 years.(Avoid freeze/thaw cycles) |
Category/Label | Other Peptides |
Background | The laminin core domain IKVAV mediates cell adhesion. Often employed for the modification of surfaces improving biocompatibility. In particular, IKVAV stimulates attachment and growth of neural stem cells. |
In Vitro | H-Ile-Lys-Val-Ala-Val-OH (0-2.5 mM, 0-48 h) induces proliferation and proliferating cell nuclear antigen (PCNA) synthesis of bone marrow mesenchymal stem cell (BMMSC). H-Ile-Lys-Val-Ala-Val-OH (5 mM, 24 h) induces the BMMSC cell cycle for cells to enter S phase from G0/G1 and arrests them from entering G2/M phase. H-Ile-Lys-Val-Ala-Val-OH (0-2.5 mM, 0-48 h) activats MAPK/ERK and PI3K/Akt signalling pathways by enhancing phosphorylation levels of ERK1/2 and Akt in the BMMSCs. |
Reference | [1] A.Farrukh et al., Stem Cell Reports, 9, 1432(2017). |
Unit | Bottle |
Specification | 1mg 5mg |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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