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My CartCAS：247044-67-3
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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| Product Type | Peptides |
| CAS | 247044-67-3 |
| Sequence(1LC) | LYLVCGERG |
| Sequence(3LC) | Leu-Tyr-Leu-Val-Cys-Gly-Glu-Arg-Gly |
| Molecular Formula | C44H72N12O13S1 |
| Molecular Weight | 1009.19 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Hormone and Related Peptides |
| Background | Insulin β Chain Peptide (15-23), also known as INS, is an insulin-derived peptide recognized by islet-associated T cells. The Insulin β Chain Peptide (15-23) tetramer stained the INS-reactive CTL clone G9C8, but neither this tetramer nor the negative control tetramer (TUM) stained the splenic CD8+ T cells from NOD or 8.3-TCRαβtransgenic NOD mice. |
| In Vitro | CD8 T-cells purified from 5- to 8-week-old G9Cα?/?.NOD mice produces IFN-γ and TNF-α in response to Insulin β Chain Peptide (15-23) (1 μg/mL, 24 h). |
| In Vivo | Insulin β Chain Peptide (15-23) (50 μg, i.p.) together with CpG 1826 oligonucleotides promotes very rapid diabetes development in G9Cα?/?.NOD mice. |
| Reference | [1] Hu, C. et al. J. Clin. Invest. 117, 3857 (2007); [2] Amrani, A. et al. Nature 406, 739 (2000). |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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