Substance P (4-11)
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Cat.No：CLP0012 Solarbio
CAS：53749-60-3
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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Other-Conjugated
Colloidal Gold Reagent
Alkaline Phosphatase(AP)-Conjugated
Colloidal Gold-Conjugated
FITC-Conjugated
Biotin-Conjugated
Purified Secondary Antibodies
Allophycocyanin(APC)-Conjugated
CY Fluorescent-Conjugated
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TGF-β/Smad
Hippo
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Inhibitors & Antagonists & Agonists
PI3K/Akt/mTOR
Endocrinology & Hormones
Protein Tyrosine Kinase/PTK
Angiogenesis
HIF
Immunology & Inflammation
Stem Cells
Apoptosis
Metabolic Enzyme & Protease
Autophagy
ER Stress
Cell Cycle
Cytoskeleton
DNA Damage & DNA Repai
Epigenetics
Ubiquitin
JAK/STAT
GPCR & G Protein
Neuronal Signal Pathway
MAPK
NF-κB
Membrane Transporter & Ion Channel
TGF-β/Smad
Hippo
Antibody-drug Conjugate/ADC Related
Others
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Instruments
Pipette & Dispenser & Pipette Dispensing Instrument
Oscillating Mixing & Stirring & Dispersing Instrument
Temperature Control & Sampling & Grinding Crushing Instrument
Sterilization & Filtration Instruments
PCR Instrument & Light Glue Instrument
Spectrophotometer
Centrifuge
Shaker
Vacuum Pump
Other Small Instruments
Product Information
| Product Type | Peptides |
| CAS | 53749-60-3 |
| Sequence(1LC) | PQQFFGLM-NH2 |
| Sequence(3LC) | Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2 |
| Molecular Formula | C46H67N11O10S1 |
| Molecular Weight | 966.17 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Substance P Related Peptides |
| Background | The octapeptide substance P (4-11), PQQFFGLM-amide, seems to be more active than the natural peptide in various pharmacological tests in vitro and in vivo. Octa-substance P was shown to be an agonist of the NK1 receptor, IC50 15 nM. |
| In Vitro | Substance P (4-11) stimulates significantly the proliferation of human T lymphocytes in vitro at concentrations of 1 nM-100 nM, as assessed by the uptake of [3H]thymidine and [3H]leucine. Substance P (4-11) elicites a strong burst of Luminol (Luminol (HY-15922))-enhanced chemiluminescence with a time course and dose-response curves in human polymorphonuclear leukocytes (PMN). |
| Reference | [1] Y.Tian et al., J. Biol. Chem., 271, 20250(1996). |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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