Gossypetin
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Cat.No：IG2600 Solarbio
CAS：489-35-0
Molecular Formula：C15H10O8
Molecular Weight：318.24
Storage：Powder:-20℃，2 years
Purity：HPLC≥90%
Appearance：Solid
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PI3K/Akt/mTOR
Endocrinology & Hormones
Protein Tyrosine Kinase/PTK
Angiogenesis
HIF
Immunology & Inflammation
Stem Cells
Apoptosis
Metabolic Enzyme & Protease
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ER Stress
Cell Cycle
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Ubiquitin
JAK/STAT
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MAPK
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TGF-β/Smad
Hippo
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> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > MAPK > Gossypetin
Product Information
| CAS | 489-35-0 |
| Name | Gossypetin |
| Molecular Formula | C15H10O8 |
| Molecular Weight | 318.24 |
| Solubility | Soluble in --- |
| Purity | HPLC≥90% |
| Appearance | Solid |
| Storage | Powder:-20℃，2 years |
| MDL | MFCD00017680 |
| SMILES | C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C(=C(C=C3O)O)O)O)O)O |
| Target Point | MKK |
| Passage | MAPK |
| Background | Gossypetin is a potent MKK3 and MKK6 inhibitor with multiple pharmacological activities, including antioxidant, antibacterial and anticancer activities. |
| Biological Activity | Gossypetin 是六羟基化的类黄酮，是一种有效的 MKK3 和 MKK6 抑制剂，可强烈减弱 MKK3/6-p38 信号传导途径，具有多种药理活性，包括抗氧化，抗菌和抗癌活性。[1] |
| Data Literature Source | [1]. Xie X，et al. Gossypetin is a novel MKK3 and MKK6 inhibitor that suppresses esophageal cancer growth in vitro and in vivo. Cancer Lett. 2019 Feb 1;442:126-136 |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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