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My Cart> Cell Biology > Cell Detection > Cell Growth Factor > Recombinant Human Bcl-2-like Protein 11/BIML
Purity：≥95% as determined by reducing SDS-PAGE.
Storage：Store at≤-70℃，6 months.with seal;3 month after opening.Avoid freeze/thaw cycles.
Appearance：Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 10% glycerol, 2mM DTT, pH8.0.
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| Appearance | Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 10% glycerol, 2mM DTT, pH8.0. |
| Purity | ≥95% as determined by reducing SDS-PAGE. |
| Storage | Store at≤-70℃，6 months.with seal;3 month after opening.Avoid freeze/thaw cycles. |
| Background | BIML is one of several splice variants of BIM，a proapoptotic protein belonging to the BH-3 domain-only subgroup of Bcl-2 family members.BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.BIML is thought to promote apoptosis by binding and inhibiting the activity of anti-apoptotic Bcl-2 family members，thereby inducing the release of cytochrome c from mitochondria.BIML is normally sequestered in an inactive conformation from anti-apoptotic Bcl-2 family members through binding to the microtubule-associated dynein motor complex.Certain apoptotic stimuli release BIML from microtubules to neutralize anti-apoptotic Bcl-2 family members，allowing for the initiation of apoptosis. |
| Source | E.coli |
| Endotoxin | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| Unit | Piece |
| Specification | 10ug 50ug 500ug 1mg |
Cell growth factor
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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