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Recombinant Human Complement component C8 gamma chain/C8G

Cat.No：P01259 Solarbio

Purity：≥95% as determined by reducing SDS-PAGE.

Storage：Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Appearance：Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

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Product Information

Appearance	Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Purity	≥95% as determined by reducing SDS-PAGE.
Storage	Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Background	Complement component C8 is a constituent of the membrane attack complex，C8 alpha，C8 beta and C8G.C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain.C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes.C8 binds to the C5B-7 complex，forming the C5B-8 complex.C5-B8 binds C9 and acts as a catalyst in the polymerization of C9.The gamma subunit seems to be able to bind retinol.Patients lacking C8 are susceptible to certain bacterial infections.
Source	E.coli
Endotoxin	Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
Unit	Piece
Specification	10ug 50ug 500ug 1mg

Cell growth factor

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.

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