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My Cart> Cell Biology > Cell Detection > Cell Growth Factor > Recombinant Human ARC/NOL3Purity：≥80% as determined by reducing SDS-PAGE.
Storage：Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Appearance：Supplied as a 0.2 μm filtered solution of 25mM TrisHCl, 1mM DTT, 1mM EDTA, 2mM β-ME, 20% Glycerol, pH 7.5.
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| Appearance | Supplied as a 0.2 μm filtered solution of 25mM TrisHCl, 1mM DTT, 1mM EDTA, 2mM β-ME, 20% Glycerol, pH 7.5. |
| Purity | ≥80% as determined by reducing SDS-PAGE. |
| Storage | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
| Background | Nucleolar protein 3 is encoded by NOL3 gene.Multiple transcript variants encoding different isoforms have been found for this gene.So far，Nucleolar protein 3 has show to have two Isoforms.Isoform 1 may be involved in RNA splicing.Isoform 2 functions as an apoptosis repressor that blocks multiple modes of cell death.It inhibits extrinsic apoptotic pathways through two different ways.Firstly，it by interacting with FAS and FADD upon FAS activation blocking death-inducing signaling complex (DISC) assembly.Secondly by interacting with CASP8 in a mitochondria localization- and phosphorylation-dependent manner，limiting the amount of soluble CASP8 available for DISC-mediated activation.It has been shown to down-regulate the enzyme activities of caspase 2，caspase 8 and tumor protein p53. |
| Source | E.coli |
| Endotoxin | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| Unit | Piece |
| Specification | 10ug 50ug 500ug 1mg |
Cell growth factor
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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