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My Cart> Cell Biology > Cell Detection > Cell Growth Factor > Recombinant Human Apoptosis Regulator Bcl-2/B-cell Lymphoma 2
Purity：≥95% as determined by reducing SDS-PAGE.
Storage：Store at≤-70℃，6 months.with seal;3 month after opening.Avoid freeze/thaw cycles.
Appearance：Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 10%Glycerol, pH8.0.
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| Appearance | Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 10%Glycerol, pH8.0. |
| Purity | ≥95% as determined by reducing SDS-PAGE. |
| Storage | Store at≤-70℃，6 months.with seal;3 month after opening.Avoid freeze/thaw cycles. |
| Background | Bcl-2 is a member of a family of proteins that regulates outer mitochondrial membrane permeability.Bcl-2 is an antiapoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol.Bcl-2 is present on the outer mitochondrial membrane and is also found on other membranes in some cell types.BCL-2 is localized to the outer membrane of mitochondria，where it plays an important role in promoting cellular survival and inhibiting the actions of pro-apoptotic proteins.The pro-apoptotic proteins in the BCL-2 family，including Bax and Bak，normally act on the mitochondrial membrane to promote permeabilization and release of cytochrome C and ROS，that are important signals in the apotosis cascade.These pro-apoptotic proteins are in turn activated by BH3-only proteins，and are inhibited by the function of BCL-2 and its relative BCL-Xl. |
| Source | E.coli |
| Endotoxin | Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test. |
| Unit | Piece |
| Specification | 10ug 50ug 500ug 1mg |
Cell growth factor
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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