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My CartCAS：312917-14-9
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 312917-14-9 |
| Name | SC-202671 |
| Molecular Formula | C20H16N2OS |
| Molecular Weight | 332.42 |
| Solubility | Soluble in DMSO ≥2mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD01005305 |
| SMILES | O=C(C1=C2C=CC=CC2=CC=C1)NC3=C(C#N)C(CCCC4)=C4S3 |
| InChIKey | WQGDQGAFSDMBLA-UHFFFAOYSA-N |
| InChI | InChI=1S/C20H16N2OS/c21-12-17-15-9-3-4-11-18(15)24-20(17)22-19(23)16-10-5-7-13-6-1-2-8-14(13)16/h1-2,5-8,10H,3-4,9,11H2,(H,22,23) |
| PubChem CID | 766949 |
| Target Point | JNK |
| Passage | MAPK |
| Background | SC-202671 is a potent JNK3 inhibitor. |
| Biological Activity | TCS JNK 5a 是一种有效的 JNK3 抑制剂，pIC50 为 6.7。TCS JNK 5a 也抑制 JNK2，pIC50为 6.5。[1] |
| IC50 | JNK3:6.7(pIC50);JNK2:6.5(pIC50)[1] |
| In Vitro | TCS JNK 5a也在超过30种激酶测定的筛选中筛选，包括Alk5，c-Fms，CDK-2，EGFR，ErbB2，GSK3β，PLK1，Src，Tie-2和VegFr2，并且无活性(pIC50 <5.0))反对所有人[1]。 |
| Data Literature Source | [1]. Angell RM，et al. N-(3-Cyano-4，5，6，7-tetrahydro-1-benzothien-2-yl)amides as potent，selective，inhibitors of JNK2 and JNK3. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1296-301. |
| Unit | Bottle |
| Specification | 5mg 10mg 25mg |
是一种有效的 JNK3 抑制剂。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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