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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > NF-κB > 3-O-Acetyl-11-keto-β-boswellic AcidCAS：67416-61-9
Molecular Formula：C32H48O5
Molecular Weight：512.72
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 67416-61-9 |
| Name | 3-O-Acetyl-11-keto-β-boswellic Acid |
| Molecular Formula | C32H48O5 |
| Molecular Weight | 512.72 |
| Solubility | Soluble in DMSO ≥1mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD03788777 |
| SMILES | C[C@@]([C@@](C1=C2)(CC[C@@](C)(CC[C@H]3C)[C@@]1([H])[C@H]3C)C)(CC[C@@]4([H])[C@@]5(C)C(O)=O)[C@@](C2=O)([H])[C@]4(CC[C@H]5OC(C)=O)C |
| Target Point | Nrf2 |
| Passage | NF-κB |
| Background | It is an activator of Nrf2. |
| Biological Activity | 3-acetyl-11-keto-β-Boswellic Acid， as known as AKBA， is a pentacyclic triterpene that suppresses 5-lipoxygenase in a selective， nonredox， enzyme-directed， and noncompetitive manner. Also， AKBA inhibits topoisomeraseⅠ and NF-κB signaling. AKBA has been studied for potential use in the control of inflammatory diseases， including arthritis and cancer.[1] |
| Data Literature Source | [1]. Syrovets，T.，Gschwend，J.，Buchele，B.，Laumonnier，Y.，Zugmaier，W.，Genze，F.，& Simmet，T. Inhibition of IκB Kinase Activity by Acetyl-boswellic Acids Promotes Apoptosis in Androgen-independent PC-3 Prostate Cancer Cells in Vitro and in Vivo. Journal of Biological Chemistry. 2004; 280(7): 6170-6180. |
| Unit | Bottle |
| Specification | 5mg 10mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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