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Application： ELISA
Reactivity：Mouse
Sensitivity：46pg/mL
Storage：2-8℃，6 months
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| Name | Mouse HER3/ERBB3 ELISA Kit |
| Storage | 2-8℃，6 months |
| Detection Target | HER3 |
| Sample Type | Serum，Plasma，Cell Culture Supernatant |
| Reactivity | Mouse |
| Application | ELISA |
| Quantitative/Qualitative | Quantitative |
| Detection Range | 93.75-6000pg/mL |
| Sensitivity | 46pg/mL |
| Precision | Both intra-plate and inter-plate variation coefficients were less than 10% |
| Recovery | 80%-120% |
| Assay Time | 3h15min |
| Swiss Prot | Q61526 |
| Gene ID | 13867 |
| Background | ErbB3，also known as Her3(human epidermal growth factor receptor3)，is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain.，and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However，its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with high affinity，and initiates the related pathway which lead to cell proliferation or differentiation. ErbB3 has been shown to implicated in numerous cancers，including prostate，bladder，and breast tumors. This protein has different isoforms derived from alternative splicing variants，and among which，the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form. |
| Unit | Kit |
| Specification | 48T 96T |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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