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Application： ELISA
Reactivity：Mouse
Sensitivity：12.5pg/mL
Storage：2-8℃，6 months
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| Name | Mouse BMP1 ELISA Kit |
| Storage | 2-8℃，6 months |
| Detection Target | BMP1 |
| Sample Type | Serum，Plasma，Cell Culture Supernatant |
| Reactivity | Mouse |
| Application | ELISA |
| Quantitative/Qualitative | Quantitative |
| Detection Range | 25-1600pg/mL |
| Sensitivity | 12.5pg/mL |
| Precision | Both intra-plate and inter-plate variation coefficients were less than 10% |
| Recovery | 80%-120% |
| Assay Time | 3h15min |
| Swiss Prot | P98063 |
| Gene ID | 12153 |
| Background | Bone morphogenetic protein 1 (BMP1)，is a protein which in humans is encoded by the BMP1 gene (1，2). There are seven isoforms of the protein created by alternate splicing. BMP1 belongs to the peptidase M12A family of bone morphogenetic proteins (BMPs). It induces bone and cartilage development. Unlike other BMPs，it does not belong to the TGFβ superfamily. It was initially discovered to work like other BMPs by inducing bone and cartilage development. It however，is a metalloprotease that cleaves the C-terminus of procollagen I，II and III. It has an astacin-like protease domain. It has been shown to cleave laminin 5 and is localized in the basal epithelial layer of bovine skin. The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily，BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP)，a secreted metalloprotease requiring calcium and needed for cartilage and bone formation，are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I，II，and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region. |
| Unit | Kit |
| Specification | 48T 96T |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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