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Methylprednisolone

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Cat.No：IM2320 Solarbio

CAS：83-43-2

Molecular Formula：C₂₂H₃₀O₅

Molecular Weight：374.47

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：≥98%

Appearance：White to off-white Solid

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Product Information

CAS	83-43-2
Name	Methylprednisolone
Molecular Formula	C₂₂H₃₀O₅
Molecular Weight	374.47
Solubility	Soluble in DMSO ≥10mg/mL
Purity	≥98%
Appearance	White to off-white Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 201-476-4
MDL	MFCD00010591
SMILES	O=C1C=C[C@]2(C)[C@@]3([H])[C@@H](O)C[C@]4(C)[C@@](O)(C(CO)=O)CC[C@@]4([H])[C@]3([H])C[C@H](C)C2=C1
InChIKey	VHRSUDSXCMQTMA-PJHHCJLFSA-N
InChI	InChI=1S/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1
PubChem CID	6741
Target Point	Glucocorticoid Receptor; ACE2; SARS-CoV
Passage	GPCR & G Protein;Metabolic Enzyme&Protease; Anti-infection
Background	Methylprednisolone is a corticosteroid that acts on glucocorticoid receptors. Methylprednisolone improves severe COVID-19 by activating ACE2 and reducing IL-6 levels.
Biological Activity	Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels[1].
Data Literature Source	[1]. Zhen Xiang，et al. Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels. Int J Biol Sci 2020; 16(13):2382-2391.
Unit	Bottle
Specification	100mg 200mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.