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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > GPCR & G Protein > AcefyllineCAS：652-37-9
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 652-37-9 |
| Name | Acefylline |
| Molecular Formula | C9H10N4O4 |
| Molecular Weight | 238.2 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 211-490-2 |
| MDL | MFCD00022832 |
| SMILES | O=C(O)CN1C=NC(N(C)C(N2C)=O)=C1C2=O |
| Target Point | Adenosine Receptor |
| Passage | GPCR & G Protein |
| Background | It is an antagonist of adenosine receptors and an activator of peptidylarginine deiminase (PAD). |
| Biological Activity | Acefylline (Theophyllineacetic acid)， a xanthine derivative， is an adenosine receptor antagonist. Acefylline is a peptidylarginine deiminase (PAD) activator. Acefylline is also a bronchodilator， which inhibits rat lung cAMP phosphodiesterase isoenzymes[1-2]. |
| Data Literature Source | [1]. Ferretti C，et al. Inhibitory effect of theophylline，theophylline-7-acetic acid，ambroxol and ambroxol-theophylline-7-acetate on rat lung cAMP phosphodiesterase isoenzymes. Int J Tissue React. 1992;14(1):31-6. [2]. Méchin MC，et，al. Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis. J Dermatol Sci. 2016 Feb;81(2):101-6. |
| Unit | Bottle |
| Specification | 100mg 200mg 500mg |
是腺苷受体的拮抗剂和肽酰精氨酸脱亚氨酶（PAD）的激活剂。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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