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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > AcitretinCAS：55079-83-9
Molecular Formula：C21H26O3
Molecular Weight：326.43
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 55079-83-9 |
| Name | Acitretin |
| Molecular Formula | C21H26O3 |
| Molecular Weight | 326.43 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 259-474-4 |
| MDL | MFCD00866632 |
| SMILES | CC(/C=C/C(C(C)=CC(OC)=C1C)=C1C)=C\C=C\C(C)=C\C(O)=O |
| Target Point | RAR/RXR |
| Passage | Metabolic Enzyme&Protease |
| Background | Acitretin is a new and effective second-generation retinoid that can be used in psoriasis-related research. |
| Biological Activity | Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin also can be used for the research of Alzheimer’s disease[1-[3]. |
| In Vitro | Acitretin(10 mg/kg; i.p. for 7 days)increases IL-6 in the central nervous system of Alzheimer’s disease model mice[3]. |
| Data Literature Source | [1]. Lee CS，et al. A review of acitretin，a systemic retinoid for the treatment of psoriasis. Expert Opin Pharmacother. 2005 Aug;6(10):1725-34. [2]. Seng r B，et al. Effects of acitretin on spermatogenesis of rats. J Eur Acad Dermatol Venereol. 2006 Jul;20(6):689-92. [3]. Guilherme MDS，et，al. The Synthetic Retinoid Acitretin Increases IL-6 in the Central Nervous System of Alzheimer Disease Model Mice and Human Patients. Front Aging Neurosci. 2019 Jul 23;11:182 |
| Unit | Bottle |
| Specification | 50mg 250mg 500mg |
阿维A是一种新型、有效的第二代类维生素A，可用于银屑病的相关研究。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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