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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > NF-κB > WedelolactoneCAS：524-12-9
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 524-12-9 |
| Name | Wedelolactone |
| Molecular Formula | C16H10O7 |
| Molecular Weight | 314.25 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-158-5 |
| MDL | MFCD07778564 |
| SMILES | O=C1C2=C(OC3=CC(O)=C(O)C=C32)C4=C(O)C=C(OC)C=C4O1 |
| Target Point | IKK |
| Passage | NF-κB |
| Background | Wedelolactone inhibited LPS-induced caspase-11 expression by directly inhibiting IKK complex. The activity of 5-lipoxygenase (5-Lox) was inhibited by oxygen radical scavenging mechanism. It has anticancer, anti-inflammatory and antioxidant activities. |
| Unit | Bottle |
| Specification | 5mg 10mg 20mg |
通过直接抑制 IKK 复合物来抑制 LPS 诱导的 caspase-11 表达。通过氧自由基清除机制抑制 5-脂氧合酶 (5-lipoxygenase， 5-Lox) 活性。具有抗癌，抗炎和抗氧化活性。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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