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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cytoskeleton > Y-27632CAS：146986-50-7
Molecular Formula：C14H21N3O
Molecular Weight：247.34
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 146986-50-7 |
| Name | Y-27632 |
| Molecular Formula | C14H21N3O |
| Molecular Weight | 247.34 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 1312995-182-4 |
| MDL | MFCD03093855 |
| SMILES | O=C([C@@H]1CC[C@]([C@H](N)C)([H])CC1)NC2=CC=NC=C2 |
| Target Point | ROCK |
| Passage | Cytoskeleton; Cell Cycle;TGF-beta/Smad;Stem Cells |
| Background | Y-27632 is a potent and selective ROCK1 (p160ROCK) inhibitor |
| Unit | Bottle |
| Specification | 5mg 10mg 50mg |
In the process of class organs culture, generally without Y - 27632. Y-27632 is a potent and selective small molecule inhibitor of ROCK1(p160ROCK), capable of targeting catalytic sites that bind ROCK-1 and ROCK-2, thereby inhibiting their kinase activity. Y-27632, which is commonly used in organoid construction, can significantly inhibit the apoptosis of stem cells caused by dissociation and improve the efficiency of clone formation, and is one of the indispensable components in the stem cell culture process.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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