{{cart_num}}
My CartCAS：161715-21-5
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to brown Solid
Qty：
Size：
| CAS | 161715-21-5 |
| Name | Tebipenem |
| Molecular Formula | C16H21N3O4S2 |
| Molecular Weight | 383.49 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to brown Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00936545 |
| SMILES | O=C(C(N1C2=O)=C(SC3CN(C4=NCCS4)C3)[C@H](C)[C@]1([H])[C@@]2([H])[C@H](O)C)O |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | Tebipenem is a broad-spectrum carbapenem antibiotic that inhibits both Gram-positive and Gram-negative bacteria. |
| Biological Activity | Tebipenem 是一种可口服的广谱的碳青霉烯类抗生素，能够抑制革兰氏阳性菌和革兰氏阴性菌，但对绿脓杆菌无作用。[1-3] |
| In Vitro | Tebipenem在低微摩尔浓度下对显色底物硝基呋喃表现出缓慢的紧密结合抑制，并且表观Km和kcat值分别为0.8μM和0.03min-1 [1]。 Tebipenem对B. pseudomallei有显著的活性，MIC50和MIC90均为2 mg/L [2]。 Tebipenem对肺炎链球菌具有良好的活性，所有肺炎链球菌分离株的MIC范围均≤0.25μg/ mL [3]。 |
| Data Literature Source | [1]. Hazra S，et al. Tebipenem，a new carbapenem antibiotic，is a slow substrate that inhibits the β-lactamase from Mycobacterium tuberculosis. Biochemistry. 2014 Jun 10;53(22):3671-8. [2]. Seenama C，et al. In vitro activity of tebipenem against Burkholderia pseudomallei. Int J Antimicrob Agents. 2013 Oct;42(4):375. [3]. Li H，et al. In vitro antibacterial activities of two novel oral antibiotics，tebipenem and cefditoren，and other comparators against community-acquired respiratory tract infection-associated bacterial pathogens: A multicentre study in China. Int J Antimicrob Agents. 2014 Jan;43(1):92-3. |
| Unit | Piece |
| Specification | 5mg 10mg 50mg |
Tebipenem 是一种广谱的碳青霉烯类抗生素，能够抑制革兰氏阳性菌和革兰氏阴性菌。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
