Dabsyl chloride
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Cat.No：ID0960 Solarbio
CAS：56512-49-3
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：Solid
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PI3K/Akt/mTOR
Endocrinology & Hormones
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HIF
Immunology & Inflammation
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ER Stress
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Pipette & Dispenser & Pipette Dispensing Instrument
Oscillating Mixing & Stirring & Dispersing Instrument
Temperature Control & Sampling & Grinding Crushing Instrument
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Spectrophotometer
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Product Information
| CAS | 56512-49-3 |
| Name | Dabsyl chloride |
| Molecular Formula | C14H14ClN3O2S |
| Molecular Weight | 323.8 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 260-235-1 |
| MDL | MFCD00007444 |
| SMILES | O=S(C1=CC=C(/N=N/C2=CC=C(N(C)C)C=C2)C=C1)(Cl)=O |
| Background | Dabsyl chloride is an amine derivatizer that can be easily monitored spectrophotometrically at 460 nm. |
| Biological Activity | Dabsyl chloride 是一种胺的衍生剂，能产生稳定的产品，可以很容易的在 460 nm 中对分光光度法进行监测；Dabsyl chloride 同时可用于标记氨基酸[1]。 |
| In Vitro | 在多个氨基存在下，Dabsyl chloride可以产生单Dabsyl和bis-Dabsyl衍生物。此外，就OPA衍生化而言，Dabsyl chloride可与伯胺和仲胺反应[1]。 |
| Cell Experiment | 从含有0.2％TDGA的500μL0.1MHCl处理来自25cm2培养瓶的皮质或纹状体区域(100mg湿重)和神经母细胞瘤细胞(SH-SY5Y)沉淀的小鼠脑样品，超声处理10分钟(仅对于脑组织)，然后以14000g离心30分钟。将上清液冷冻干燥。将50μL反应缓冲液和100μL15mMDabsyl氯化物加入管中并衍生化。 |
| Data Literature Source | [1]. Francioso A， et al. HPLC Determination of Bioactive Sulfur Compounds， Amino Acids and Biogenic Amines in Biological Specimens. Adv Exp Med Biol. 2017; 975:535-549 |
| Unit | Piece |
| Specification | 50mg 10mM*1mL in DMSO 100mg 200mg |
Dabsyl chloride 是一种胺的衍生剂，可以很容易的在 460 nm 中对分光光度法进行监测。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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