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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > NF-κB > StachydrineCAS：471-87-4
Molecular Formula：C7H13NO2
Molecular Weight：143.18
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 471-87-4 |
| Name | Stachydrine |
| Molecular Formula | C7H13NO2 |
| Molecular Weight | 143.18 |
| Solubility | Soluble in Water/DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 207-445-1 |
| MDL | MFCD09837899 |
| SMILES | C[N+]1(C)[C@H](C([O-])=O)CCC1 |
| Target Point | NF-kB |
| Passage | NF-κB |
| Background | Stachydrine, the main component of the Chinese herb Leonurus, inhibits the NF-κB signaling pathway. |
| Biological Activity | Stachydrine是中国草本植物益母草的主要成分，用于促进血液循环和消除血瘀。Stachydrine 可抑制 NF-κB 信号通路。[1-5] |
| Data Literature Source | [1]. Guo W，et al. Effect of Leonurus stachydrine on myocardial cell hypertrophy. Zhong Yao Cai. 2012 Jun;35(6):940-3. [2]. Yin J，et al. Stachydrine，a major constituent of the Chinese herb leonurus heterophyllus sweet，ameliorates human umbilical vein endothelial cells injury induced by anoxia-reoxygenation. Am J Chin Med. 2010;38(1):157-71. [3]. Rathee P，et al. In vitro anticancer activity of stachydrine isolated from Capparis decidua on prostate cancer cell lines. Nat Prod Res. 2012;26(18):1737-40. [4]. Zhang C，et al. Effects of stachydrine on norepinephrine-induced neonatal rat cardiac myocytes hypertrophy and intracellular calcium transients. BMC Complement Altern Med. 2014 Dec 8;14:474. [5]. Zhang C，et al. Effect of stachydrine on endoplasmic reticulum stress-induced apoptosis in rat kidney after unilateral ureteral obstruction. J Asian Nat Prod Res. 2013;15(4):373-81. |
| Unit | Piece |
| Specification | 10mg 10mM*1mL in DMSO 20mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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