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My CartCAS：547-32-0
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 547-32-0 |
| Name | Sodium sulfadiazine |
| Molecular Formula | C10H9N4NaO2S |
| Molecular Weight | 272.26 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 208-919-0 |
| MDL | MFCD00067333 |
| SMILES | O=S(C1=CC=C(N)C=C1)(NC2=NC=CC=N2)=O.[Na] |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | Sulfadiazine sodium belongs to the sulfonamide class of antibiotics. |
| Biological Activity | Sodium Sulfadiazine (Sulfadiazin-natrium)是sulfadiazine的钠盐形式，一种具有中效抑菌作用的合成sulfanilamide衍生物。Sulfadiazine sodium 也对弓形虫病有效。[1] |
| In Vivo | 本研究评价磺胺嘧啶钠和乙胺嘧啶治疗不同非典型弓形虫株急性感染小鼠的疗效。瑞士小鼠感染了7株弓形虫。用磺胺嘧啶钠10-640毫克/千克/天、乙胺嘧啶3-200毫克/千克/天或两种低剂量药物联合治疗感染小鼠。采用描述性分析评估钠和/或乙胺嘧啶敏感性与基因型之间的关系。TgCTBr4和TgCTBr17菌株(108基因型)对钠或乙胺的敏感性较低。TgCTBr1和TgCTBr25菌株(基因型206)对吡咯的敏感性相似，但对钠的敏感性不明显。TgCTBr9菌株(基因型11)是唯一对两种药物治疗都有高易感性的菌株[1]。 |
| Data Literature Source | [1]. Kopmann C，et al. Abundance and transferability of antibiotic resistance as related to the fate of sulfadiazine in maize rhizosphere and bulk soil. FEMS Microbiol Ecol. 2013 Jan;83(1):125-34. |
| Unit | Piece |
| Specification | 20mg 50mg 100mg |
Sulfadiazine sodium 属于磺胺类抗生素。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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