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My CartCAS：327-57-1
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 327-57-1 |
| Name | L-Norleucine |
| Molecular Formula | C6H13NO2 |
| Molecular Weight | 131.17 |
| Solubility | Soluble in Water |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 206-321-4 |
| MDL | MFCD00064423 |
| SMILES | N[C@@H](CCCC)C(O)=O |
| InChIKey | LRQKBLKVPFOOQJ-YFKPBYRVSA-N |
| InChI | InChI=1S/C6H13NO2/c1-2-3-4-5(7)6(8)9/h5H,2-4,7H2,1H3,(H,8,9)/t5-/m0/s1 |
| PubChem CID | 21236 |
| Target Point | Others |
| Passage | Others |
| Background | L-Norleucine is an isomer of leucine. |
| Biological Activity | L-Norleucine 是亮氨酸的异构体，能够影响骨骼肌中蛋白质的合成[1-2]。 |
| In Vitro | L-正亮氨酸是亮氨酸的异构体，特别影响骨骼肌中的蛋白质合成[1]。 L-正亮氨酸具有抗病毒活性。 L-正亮氨酸与hnRNPA2/B1蛋白相互作用，抑制两种E-cadherin抑制剂Twist1和Snail的表达，促进E-cadherin的表达，从而抑制肿瘤转移[2]。 |
| Data Literature Source | [1]. Schott KJ，et al. On the role of branched-chain amino acids in protein turnover of skeletal muscle. Studies in vivo with L-norleucine. Z Naturforsch C. 1985 May-Jun;40(5-6):427-37. [2]. He T，et al. The homeostasis-maintaining metabolites from bacterial stress response to bacteriophage infection suppress tumor metastasis. Oncogene. 2018 Jun 20 |
| Unit | Bottle |
| Specification | 20mg 50mg 100mg |
L-Norleucine 是亮氨酸的异构体。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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