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My CartCAS：112246-15-8
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 112246-15-8 |
| Name | 20(R)Ginsenoside Rh2 |
| Molecular Formula | C36H62O8 |
| Molecular Weight | 622.87 |
| Solubility | Soluble in DMSO |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 2017-001-1 |
| MDL | MFCD22200425 |
| SMILES | O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1O[C@H]2CC[C@]3(C)[C@@]4([H])C[C@@H](O)[C@@H]5[C@@H]([C@](C)(O)CC/C=C(C)\C)CC[C@](C)5[C@@](C)4CC[C@@]3([H])C2(C)C |
| Target Point | MMP |
| Passage | Metabolic Enzyme&Protease |
| Background | 20(R)Ginsenoside Rh2 is a matrix metalloproteinase (MMP) inhibitor. |
| Biological Activity | 20(R)-Ginsenoside Rh2， a matrix metalloproteinase (MMP) inhibitor， acts as a cell antiproliferator. It has anticancer effects via blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis， and has anti-inflammatory and antioxidative activity[1-3]. |
| Data Literature Source | [1]. Choi WY，et al. Anti-inflammatory，antioxidative and matrix metalloproteinase inhibitory properties of 20(R)-ginsenoside Rh2 in cultured macrophages and keratinocytes. J Pharm Pharmacol. 2013 Feb;65(2):310-6. [2]. Chung KS，et al. Ginsenoside Rh2 induces cell cycle arrest and differentiation in human leukemia cells by upregulating TGF-β expression. Carcinogenesis. 2013 Feb;34(2):331-40. [3]. Choi S，et al. Ginsenoside Rh2-mediated G1 phase cell cycle arrest in human breast cancer cells is caused by p15 Ink4B and p27 Kip1-dependent inhibition of cyclin-dependent kinases. Pharm Res. 2009 Oct;26(10):2280-8. |
| Unit | Bottle |
| Specification | 5mg 10mg 20mg |
是基质金属蛋白酶（MMP）抑制剂。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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