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My CartCAS：10049-83-9
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
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| CAS | 10049-83-9 |
| Name | Pyrithioxin dihydrochloride |
| Molecular Formula | C16H22Cl2N2O4S2 |
| Molecular Weight | 441.39 |
| Solubility | Soluble in Water |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 233-178-5 |
| MDL | MFCD00057357 |
| SMILES | OCC1=C(CSSCC2=C(CO)C(O)=C(C)N=C2)C=NC(C)=C1O.[H]Cl.[H]Cl |
| InChIKey | HRZWYHGGJOWGRI-UHFFFAOYSA-N |
| InChI | InChI=1S/C16H20N2O4S2.2ClH/c1-9-15(21)13(5-19)11(3-17-9)7-23-24-8-12-4-18-10(2)16(22)14(12)6-20;;/h3-4,19-22H,5-8H2,1-2H3;2*1H |
| PubChem CID | 82325 |
| Target Point | Others |
| Passage | Others |
| Background | It is a neurodynamic compound that promotes the metabolism of glucose and amino acids in the brain. |
| Biological Activity | Pyrithioxin dihydrochloride is a neurodynamic compound, combined with a short period of hyperventilation (HV) was applied in cerebral infarct patients with Hemiplegia.[1] |
| In Vivo | Chronic treatment(15 days)of aged(22 months)female NMRI mice with pyritinol(200 mg/kg)restored the reduced density of N-methyl-D-aspartate receptors in the aged mouse brain. [2] |
| Data Literature Source | [1]. Stoica E，et al. Facilitation through hyperventilation of therapeutic effect of pyrithioxin in cerebral infarct patients. Eur Neurol. 1975;13(4):285-303. [2] H Hartmann，et al. Neuropharmacology. 1993 Feb;32(2):119-2 |
| Unit | Bottle |
| Specification | 100mg 10mM*1mL in Water |
是一种神经动力化合物， 促进脑内葡萄糖及氨基酸的代谢。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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