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Application：ELISA
Reactivity：Rat
Sample Type：Serum，Plasma，Cell Culture Supernatant
Sensitivity：5pg/mL
Storage：2-8℃，6 months
Gene ID：83470
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| Name | Rat BMP1 ELISA Kit |
| Storage | 2-8℃，6 months |
| Detection Target | BMP1 |
| Sample Type | Serum，Plasma，Cell Culture Supernatant |
| Reactivity | Rat |
| Application | ELISA |
| Quantitative/Qualitative | Quantitative |
| Detection Range | 25-1600pg/mL |
| Sensitivity | 5pg/mL |
| Precision | Both intra-plate and inter-plate variation coefficients were less than 10% |
| Recovery | 80%-120% |
| Swiss Prot | A6HTK6 |
| Gene ID | 83470 |
| Background | Bone morphogenetic protein 1 (BMP-1)，also known as procollagen C-proteinase (PCP)，is a zinc protease of the astacin family. BMP-1/PCP plays a key role in formation of extracellular matrix (ECM) by converting precursor proteins into their mature and functional forms. The precursor proteins identified as substrates for BMP-1/PCP include collagens，biglycan，laminin 5，dentin matrix protein-1，and lysyl oxidase. There are six alternatively spliced forms known to be derived from the BMP-1 gene，and isoform 1 consisting of residues 1 to 730 was expressed. The secreted and purified protein does not contain the signal peptide (amino acid residues 1?22) and pro domain (residues 23?120)，but contain protease (residues 121?321)，CUB I (residues 322?434)，CUB II (residues 435?546)，EGF-like (residues 547?588) and CUB III (residues 591?703) domains. The pro domain is apparently cleaved by a furin-like proprotein convertase. The purified BMP-1/PCP is an active protease and its peptidase activity can be determined as described above. The purified BMP-1/PCP is predicted to possess procollagen C-proteinase activity because it contains the minimal domain structure required. |
| Unit | Kit |
| Specification | 48T 96T |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
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