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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Cytoskeleton > Cyclo(RADfK)CAS：756500-23-9
Molecular Formula：C28H43N9O7
Molecular Weight：617.7
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 756500-23-9 |
| Name | Cyclo(RADfK) |
| Molecular Formula | C28H43N9O7 |
| Molecular Weight | 617.7 |
| Solubility | Soluble in Water |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| SMILES | O=C([C@@H](CC1=CC=CC=C1)NC([C@]([H])(CC(O)=O)NC([C@H](C)N2)=O)=O)N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C2=O)=O |
| InChIKey | SMFHXHGBDFBWOX-OFOKGCAXSA-N |
| InChI | InChI=1S/C28H43N9O7/c1-16-23(40)36-21(15-22(38)39)27(44)37-20(14-17-8-3-2-4-9-17)26(43)35-18(10-5-6-12-29)25(42)34-19(24(41)33-16)11-7-13-32-28(30)31/h2-4,8-9,16,18-21H,5-7,10-15,29H2,1H3,(H,33,41)(H,34,42)(H,35,43)(H,36,40)(H,37,44)(H,38,39)(H4,30,31,32)/t16-,18-,19-,20+,21+/m0/s1 |
| PubChem CID | 95565988 |
| Target Point | Integrin |
| Passage | Cytoskeleton |
| Background | Cyclo(RADfK) is a selective α(v)β(3) integrin ligand for the study of angiogenesis |
| Biological Activity | Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research， therapy， and diagnosis of neoangiogenesis[1]. |
| IC50 | Integrin[1]. |
| In Vitro | Cyclo(RADfK) is a negative control for the cyclo (-RGDfK-)， the RGD peptide. RGD peptides are modulators of cell adhesion and are recognized by several members of the integrin family[1]. |
| Data Literature Source | [1]. Srivatsan A，et al. Conjugation of cRGD peptide to chlorophyll a based photosensitizer (HPPH) alters its pharmacokinetics withenhanced tumor-imaging and photosensitizing (PDT) efficacy. Mol Pharm. 2011 Aug 1;8(4):1186-1197. |
| Unit | Bottle |
| Specification | 1mg |
是一种选择性α(v)β(3)整联蛋白配体，可用于血管生成方向的研究
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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