{{cart_num}}
My CartCAS：1011301-27-1
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 1011301-27-1 |
| Name | Tenovin-3 |
| Molecular Formula | C18H21N3OS |
| Molecular Weight | 327.44 |
| Solubility | Soluble in DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-256-5 |
| MDL | MFCD25976437 |
| SMILES | O=C(NC(NC1=CC=C(N)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2 |
| InChIKey | NLAXTZPUTNGRDU-UHFFFAOYSA-N |
| InChI | InChI=1S/C18H21N3OS/c1-18(2,3)13-6-4-12(5-7-13)16(22)21-17(23)20-15-10-8-14(19)9-11-15/h4-11H,19H2,1-3H3,(H2,20,21,22,23) |
| PubChem CID | 24772097 |
| Target Point | p53 |
| Passage | Apoptosis |
| Background | Tenovin-3 is a class of p53 activators that protect p53 from MDM2-mediated degradation by inhibiting SirT1. |
| Biological Activity | Tenovin-3 is a p53 activator[1] |
| Data Literature Source | [1]. Lain S，et al. Discovery，in vivo activity，and mechanism of action of a small-molecule p53 activator. Cancer Cell. 2008 May;13(5):454-63. |
| Unit | Bottle |
| Specification | 5mg |
是一类p53激活剂，通过抑制SirT1，保护p53免于MDM2介导的降解。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Manual Download
