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My CartCAS：95-25-0
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 95-25-0 |
| Name | Chlorzoxazone |
| Molecular Formula | C7H4ClNO2 |
| Molecular Weight | 169.57 |
| Solubility | Soluble in DMSO ≥25mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 202-403-9 |
| MDL | MFCD00005717 |
| SMILES | O=C1OC2=CC=C(Cl)C=C2N1 |
| InChIKey | TZFWDZFKRBELIQ-UHFFFAOYSA-N |
| InChI | InChI=1S/C7H4ClNO2/c8-4-1-2-6-5(3-4)9-7(10)11-6/h1-3H,(H,9,10) |
| PubChem CID | 2733 |
| Target Point | Cytochrome P450 |
| Passage | Metabolic Enzyme&Protease |
| Background | Chlorzoxazone is a centrally acting muscle relaxant. |
| Biological Activity | Chlorzoxazone (CLZ) is currently being used as a marker substrate in vitro/vivo studies to quantify cytochrome P450 2E1 (CYP2E1) activity in humans. [1] Chlorzoxazone is a centrally acting muscle relaxant.[2] |
| Data Literature Source | [1]. Yamamura Y，et al. Comprehensive kinetic analysis and influence of reaction components for chlorzoxazone 6-hydroxylation in human liver microsomes with CYP antibodies. Xenobiotica. 2015 Apr;45(4):353-360. [2]. Cao Y，Dreixler JC，Roizen JD，Roberts MT，Houamed KM. Modulation of recombinant small-conductance Ca(2+)-activated K(+) channels by the muscle relaxant chlorzoxazone and structurally related compounds. J Pharmacol Exp Ther. 2001 Mar;296(3):683-9. |
| Unit | Bottle |
| Specification | 10mM*1mL in DMSO 25mg 50mg 100mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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