Phorbol 12-Myristate 13-Acetate
Cat.No：P6741 Solarbio
CAS：16561-29-8
Appearance：Crystalline solid
Storage：Store at -20℃，avoid light，2 years.
Purity：≥98%
Qty：
-
+
Size：
{{cart_num}}
My CartTel: +86 010 50973105
Products
Secondary Antibodies
SAlexa Fluor-Conjugated
Other Fluorescent-Conjugated
Other-Conjugated
Colloidal Gold Reagent
Alkaline Phosphatase(AP)-Conjugated
Colloidal Gold-Conjugated
FITC-Conjugated
Biotin-Conjugated
Purified Secondary Antibodies
Allophycocyanin(APC)-Conjugated
CY Fluorescent-Conjugated
Phycoglobin(PE)-Conjugated
RBTIC-Conjugated
Peroxidase (HRP)-Conjugated
Secondary Antibodies
SAlexa Fluor-Conjugated
Other Fluorescent-Conjugated
Other-Conjugated
Colloidal Gold Reagent
Alkaline Phosphatase(AP)-Conjugated
Colloidal Gold-Conjugated
FITC-Conjugated
Biotin-Conjugated
Purified Secondary Antibodies
Allophycocyanin(APC)-Conjugated
CY Fluorescent-Conjugated
Phycoglobin(PE)-Conjugated
RBTIC-Conjugated
Peroxidase (HRP)-Conjugated
Inhibitors & Antagonists & Agonists
PI3K/Akt/mTOR
Endocrinology & Hormones
Protein Tyrosine Kinase/PTK
Angiogenesis
HIF
Immunology & Inflammation
Stem Cells
Apoptosis
Metabolic Enzyme & Protease
Autophagy
ER Stress
Cell Cycle
Cytoskeleton
DNA Damage & DNA Repai
Epigenetics
Ubiquitin
JAK/STAT
GPCR & G Protein
Neuronal Signal Pathway
MAPK
NF-κB
Membrane Transporter & Ion Channel
TGF-β/Smad
Hippo
Antibody-drug Conjugate/ADC Related
Others
Inhibitors & Antagonists & Agonists
PI3K/Akt/mTOR
Endocrinology & Hormones
Protein Tyrosine Kinase/PTK
Angiogenesis
HIF
Immunology & Inflammation
Stem Cells
Apoptosis
Metabolic Enzyme & Protease
Autophagy
ER Stress
Cell Cycle
Cytoskeleton
DNA Damage & DNA Repai
Epigenetics
Ubiquitin
JAK/STAT
GPCR & G Protein
Neuronal Signal Pathway
MAPK
NF-κB
Membrane Transporter & Ion Channel
TGF-β/Smad
Hippo
Antibody-drug Conjugate/ADC Related
Others
Instruments
Pipette & Dispenser & Pipette Dispensing Instrument
Oscillating Mixing & Stirring & Dispersing Instrument
Temperature Control & Sampling & Grinding Crushing Instrument
Sterilization & Filtration Instruments
PCR Instrument & Light Glue Instrument
Spectrophotometer
Centrifuge
Shaker
Vacuum Pump
Other Small Instruments
Instruments
Pipette & Dispenser & Pipette Dispensing Instrument
Oscillating Mixing & Stirring & Dispersing Instrument
Temperature Control & Sampling & Grinding Crushing Instrument
Sterilization & Filtration Instruments
PCR Instrument & Light Glue Instrument
Spectrophotometer
Centrifuge
Shaker
Vacuum Pump
Other Small Instruments
Your Position: Home
> Biochemical Reagents > Other Biochemical Reagents > Phorbol 12-Myristate 13-Acetate
Product Information
| Name | Phorbol 12-myristate 13-acetate |
| CAS | 16561-29-8 |
| Molecular Formula | C36H56O8 |
| Molecular Weight | 616.8 |
| Storage | Store at -20℃，avoid light，2 years. |
| Appearance | Crystalline solid |
| Purity | ≥98% |
| Source | Penicillium |
| Solubility | 10mg/mL in DMSO |
| Unit | Bottle |
| Specification | 1mg 5mg |
PMA (synonymous name: TPA) is a phorbol ester PKC activator widely used in vitro and in vivo. PMA binds PKC(Ki =2.6 nM) and activates its function, showing an extremely broad inhibition spectrum in both cells and tissues. PMA could inhibit Fas-induced apoptosis, but could also induce apoptosis in HL-60 cells. PMA is a highly effective tumor promoter and can promote skin tumor formation in mice. Although PMA is highly toxic, it still shows anti-leukemia and anti-neutropenia activities in humans.
Use concentration:
The specific concentration of PMA should be referred to the relevant literature, and explored and optimized according to the experimental conditions (such as experimental purpose, cell type, culture characteristics, etc.).
Preparation and storage:
Soluble in organic solvents such as ethanol and DMSO. DMSO up to 100mM.
This product may not be suitable for inducing the differentiation of THP-1 cells into macrophages.
Note: PMA can be dissolved in DMSO, and the solution dissolved in DMSO is used as storage solution. The solution diluted with water reagent can not be stored at -20 degrees and is protected from light. It is recommended to use current dilution.
Note：Product information may be optimized and upgraded. Please refer to the actual label information for accuracy.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Experimental Images
Sorry, there is no more information.
Related Products
Sorry, there is no more information.
Related Paper
The Antitumor Potential of λ-Carrageenan Oligosaccharides on Gastric Carcinoma by Immunomodulation
Click to check >>Author：Min Tang, Leilei Zhai, Juanjuan Chen, Feng Wang, Haimin Chen, Wei Wu
IF：6.7060
Publish_to：Nutrients
PMID：37432179
SARS-CoV-2 N Protein Triggers Acute Lung Injury via Modulating Macrophage Activation and Infiltration in in vitro and in vivo
Click to check >>Author：Dengming Lai, Kun Zhu, Sisi Li, Yi Xiao, Qi Xu, Yisheng Sun, Pingping Yao, Daqing Ma, Qiang Shu
IF：4.6310
Publish_to：Journal of Inflammation Research
PMID：37143821
Lactobacillus Plantarum NC8 and its metabolite acetate alleviate type 1 diabetes via inhibiting NLRP3
Click to check >>Author：Yuting Zhang, Yanning Li, Xiuquan Wang, Jingshu Huang, Xize Feng, Chunwei Shi, Wentao Yang, Yanlong Jiang, Xin Cao, Jianzhong Wang, Haibin Huang, Yan Zeng, Nan Wang, Guilian Yang, Chunfeng Wang
IF：3.8000
Publish_to：MICROBIAL PATHOGENESIS
PMID：37422174
Follicular fluid exosomes regulate OVGP1 secretion in yak oviduct epithelial cells via autophagy in vitro
Click to check >>Author：Fang Wang, Xiu-Li Zhang, Jing-Ya Yang, Gang Zhou
IF：1.6000
Publish_to：JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
PMID：37340721
Technical Q&A
Service for Scientific Research, Responsible for the Life Science
Contact Us
Address: No 85, Liandong U Valley, Middle Zone, 101102, Tongzhou Dist,
Beijing, China
Tel: +86 010 50973105
Email: [email protected]
Order Guide
Service Guarantee
Resources Download
Copyright © 2005-2021 Solarbio all rights reserved.
为啥这个不能用于诱导THP-1细胞分化，是证实了吗？它和货号IP1010的有啥区别？ 2023-05-27 21:13:39
Administrator您好，诱导细胞分化建议使用IP1010，IP1010这个纯度等级更高。
用DMSO稀释后的可以在-20保存多久啊 2022-08-17 22:40:41
Administrator-20℃保存建议在一个月内使用，此外试剂存储还要注意避光，试剂对光也是有一定的敏感性的。
请问可以存放在负80吗 2022-07-05 10:30:03
Administrator可以-80℃保存