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My CartCAS：64-75-5
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：Light yellow to yellow Solid
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| CAS | 64-75-5 |
| Name | Tetracycline Hydrochloride |
| Molecular Formula | C22H24N2O8·HCl |
| Molecular Weight | 480.9 |
| Solubility | Soluble in Water/DMSO ≥10mg/mL |
| Purity | HPLC≥98% |
| Appearance | Light yellow to yellow Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 200-593-8 |
| MDL | MFCD00078142 |
| SMILES | O[C@@]1(C(C(C(N)=O)=C2O)=O)[C@@]([C@@H]2N(C)C)([H])C[C@@]([C@](O)(C3=CC=C4)C)([H])C(C(C3=C4O)=O)=C1O.Cl |
| InChIKey | YCIHPQHVWDULOY-FMZCEJRJSA-N |
| InChI | InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1 |
| PubChem CID | 54704426 |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | Tetracycline hydrochloride is a broad-spectrum antibiotic. Tetracycline inhibits bacterial protein synthesis by preventing the binding of aminoacyl-tRNA to bacterial ribosomes. |
| Biological Activity | Tetracycline hydrochloride是一种广谱抗生素，用于治疗多种感染。[1] |
| In Vitro | 四环素类是广谱药物，具有抗多种革兰氏阳性和革兰氏阴性细菌，非典型生物如衣原体，支原体和立克次氏体以及原生动物寄生虫的活性。四环素通过阻止氨酰基-tRNA与细菌核糖体的结合来抑制细菌蛋白质合成。四环素通过OmpF和OmpC孔蛋白通道穿过革兰氏阴性肠细菌的外膜，作为带正电荷的阳离子(可能是镁)- 四环素配位络合物[1]。 |
| In Vivo | 四环素类可用于治疗家禽，牛，绵羊和猪的感染。在一些情况下，例如，对于在商业农场饲养的大量家禽的治疗性处理，抗生素直接添加到饲料或水中或者可以在气溶胶中施用。四环素可用作促进生长或促进生长。四环素用于水产养殖，以控制鲑鱼，鲶鱼和龙虾的感染[2]。 |
| Data Literature Source | [1]. Chopra I，et al.Tetracycline antibiotics: mode of action，applications，molecular biology，and epidemiology ofbacterial resistance.Microbiol Mol Biol Rev. 2001 Jun;65(2):232-60 |
| Unit | Bottle |
| Specification | 100mg 10mM*1mL in DMSO 200mg 500mg |
Tetracycline hydrochloride是一种广谱抗生素。四环素通过阻止氨酰基-tRNA与细菌核糖体的结合来抑制细菌蛋白质合成。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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Zl A, et al. Chemical Engineering Journal, 394.
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