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My CartCAS：3810-74-0
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to yellow Solid
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| CAS | 3810-74-0 |
| Name | Streptomycin Sulfate |
| Molecular Formula | 2(C21H39N7O12)·3(H2SO4) |
| Molecular Weight | 1457.38 |
| Solubility | Soluble in Water ≥5mg/mL |
| Purity | ≥98% |
| Appearance | White to yellow Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 223-286-0 |
| MDL | MFCD00037023 |
| SMILES | O[C@@]1(C=O)[C@H]([C@@H](O[C@H]1C)O[C@]([C@@H]([C@@H](O)[C@@H]2NC(N)=N)O)([H])[C@H]([C@@H]2O)NC(N)=N)O[C@@](O[C@@H](CO)[C@H](O)[C@H]3O)([H])[C@H]3NC.[1.5H2SO4] |
| InChIKey | QTENRWWVYAAPBI-YCRXJPFRSA-N |
| InChI | InChI=1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;;;/m00.../s1 |
| PubChem CID | 19648 |
| Target Point | Bacterial |
| Passage | Anti-infection |
| Background | Streptomycin sulfate is an aminoglycoside antibiotic that inhibits protein synthesis. |
| Biological Activity | Streptomycin sulfate 是一种氨基糖苷类抗生素，能够抑制蛋白质的合成。[1-2] |
| In Vitro | 随着生长培养基中CV浓度的增加，菌株RB1显示出对链霉素的增强的易感性。随着生长培养基中CV浓度的增加，细胞色素aa3水平和链霉素敏感性均增加。细胞色素aa3是枯草芽孢杆菌积累链霉素所必需的[1]。链霉素影响tRNA选择。链霉素抗性突变通常映射到蛋白质S12，并且大多数这些变体在tRNA选择过程中表现出增加的区分[2]。 |
| Data Literature Source | [1]. McEnroe AS，et al. Correlation between cytochrome aa3 concentrations and streptomycin accumulation in Bacillus subtilis. Antimicrob Agents Chemother. 1984 Oct;26(4):507-12. [2]. Sharma，D.，et al.，Mutational analysis of S12 protein and implications for the accuracy of decoding by the ribosome. J Mol Biol，2007. 374(4): p. 1065-76. |
| Unit | Bottle |
| Specification | 100mg 10mM*1mL in Water 500mg |
Streptomycin sulfate 是一种氨基糖苷类抗生素，能够抑制蛋白质的合成。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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