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My CartCAS：16595-80-5
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 16595-80-5 |
| Name | Levamisole Hydrochloride |
| Molecular Formula | C11H12N2S·HCl |
| Molecular Weight | 240.75 |
| Solubility | Soluble in Water/DMSO ≥10mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 240-654-6 |
| MDL | MFCD00012675 |
| SMILES | [H]Cl.C12=N[C@@H](C3=CC=CC=C3)CN1CCS2 |
| InChIKey | LAZPBGZRMVRFKY-HNCPQSOCSA-N |
| InChI | InChI=1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1 |
| PubChem CID | 27944 |
| Target Point | Parasite;HSV |
| Passage | Anti-infection |
| Background | Levamisole Hydrochloride is used as an insect repellent and immunomodulator, and has anti-HSV activity as well. |
| Unit | Bottle |
| Specification | 50mg 10mM*1mL in DMSO 100mg 500mg |
Examples of using this product（for reference only）
In Vitro:
Cell（worms；10 mM levamisole hydrochloride）:
In brief, worms synchronized to the L4 stage were transferred to NGM OP50 plates with DMSO(control) or with CA (5, 10, 20 μM) or rapamycin (2 nM) for 5 d. Worms were then transferred to NGM OP50 plates containing 5 mM paraquat for 24 h, followed by an M9 buffer solution. Worms were then anesthetized with 10 mM levamisole hydrochloride and fixed on 2% agarose slides (25 individuals per group). The entry of DAF-16 into the nuclei was observed and imaged by fluorescence microscopy with a 10x objective lens (λex530/40 nm, λem575–640 nm) and the distribution of cytoplasm, intermediate, and nucleus was statistically analyzed.
Reference：
Zhou L, Liu J, Bu LL, Liao DF, Cheng SW, Zheng XL. Curcumin Acetylsalicylate Extends the Lifespan of Caenorhabditis elegans. Molecules. 2021 Oct 31;26(21):6609. doi: 10.3390/molecules26216609. PMID: 34771018; PMCID: PMC8586958.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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