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My CartCAS：107-43-7
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：HPLC≥98%
Appearance：White to off-white Solid
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| CAS | 107-43-7 |
| Name | Betaine |
| Molecular Formula | C5H11NO2 |
| Molecular Weight | 117.15 |
| Solubility | Soluble in Water ≥50mg/mL |
| Purity | HPLC≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 203-490-6 |
| MDL | MFCD00012123 |
| SMILES | O=C([O-])C[N+](C)(C)C |
| InChIKey | KWIUHFFTVRNATP-UHFFFAOYSA-N |
| InChI | InChI=1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3 |
| PubChem CID | 247 |
| Target Point | Others |
| Passage | Others |
| Background | Betaine is a highly efficient methyl donor, which can replace methionine and choline as a methyl donor. It can ensure the methyl needs of various biochemical reactions in animals to ensure the normal synthesis and metabolism of nucleic acids and proteins. |
| Unit | Bottle |
| Specification | 20mg 10mM*1mL in Water 100mg 250mg |
Betaine, a kind of alkaloid, is an efficient methyl donor, which can replace methionine and choline as methyl donors. It can ensure that methyl groups involved in various biochemical reactions in animals are needed to ensure the normal synthesis and metabolism of nucleic acids and proteins; It can regulate cell osmotic pressure, reduce stress response, and ensure the normal growth of animals.
Examples of using this product（for reference only）
In Vivo：
Mice (Five-week-old C57BL/6 similar weight male mice; 2% w/v betaine in water）:
At week 8, the mice were randomly divided into 3 groups (n= 6 in each group), balanced to achieve a similar average body weight. The NFD group was fed with a normal fat diet (11.7% kcal fat). The HFD group was fed a high fat diet (45% kcal fat). The HB (high fat diet adding betaine) group was fed a high fat diet with betaine in drinking water (2% w/v; Beijing Solarbio Science & Technology Co., Ltd., Beijing, China).
Reference：
Huang T, Yu J, Luo Z, Yu L, Liu S, Wang P, Jia M, Wu T, Miao W, Zhou L, Song Z, Zhang H, Li Y. Translatome analysis reveals the regulatory role of betaine in high fat diet (HFD)-induced hepatic steatosis. Biochem Biophys Res Commun. 2021 Oct 20;575:20-27. doi: 10.1016/j.bbrc.2021.08.058. Epub 2021 Aug 25. PMID: 34454176.
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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Huang T, et al. Biochem Biophys Res Commun. 2021 Oct 20;575:20-27.
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