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My CartReactivity：Human,Rat,Mouse
Application：WB,IHC
Clone Type：Polyclonal Antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Gene ID：5551
Host：Rabbit
Qty：
Size：
| Name | Anti-PRF1 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | WB 1:1000-3000. IHC 1:50-200. |
| Target | PRF1 |
| Background | This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes， multiple sclerosis， lymphomas， autoimmune lymphoproliferative syndrome (ALPS)， aplastic anemia， and familial hemophagocytic lymphohistiocytosis type 2 (FHL2)， a rare and lethal autosomal recessive disorder of early childhood. |
| Swiss Prot | P14222 |
| Gene ID | 5551 |
| Subcellular Location | Cytoplasm Cell membrane |
| Immunogen | Recombinant protein of human PRF1 |
| Public Immunogen Range | 100-450aa |
| Calculated MW | 61kDa |
| Observed MW | 70kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol， 0.03% Proclin300， 0.5% BSA， pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | 支 |
| Specification | 20ul 50ul 100ul |
| Reactivity | Human Mouse Rat |
| Application | WB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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