Anti-KIR3DS1 Polyclonal Antibody
Cat.No:K115482P Solarbio
Reactivity:Human
Application: WB
Storage:Store at -20℃. Avoid freeze / thaw cycles.
Host:Rabbit
Qty:
Size:
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My CartReactivity:Human
Application: WB
Storage:Store at -20℃. Avoid freeze / thaw cycles.
Host:Rabbit
Qty:
Size:
Name | Anti-KIR3DS1 Polyclonal Antibody |
Host | Rabbit |
Clone Type | Polyclonal Antibody |
Subtype | IgG |
Dilution Ratio | WB 1:1000-3000. |
Target | KIR3DS1 |
Background | Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes,although several framework genes are found in all haplotypes (KIR3DL3,KIR3DP1,KIR3DL4,KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM),while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules;thus,KIR proteins are thought to play an important role in regulation of the immune response. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Swiss Prot | Q14943 |
Gene ID | 3813 |
Subcellular Location | Cell membrane |
Immunogen | Recombinant protein of human KIR3DS1 |
Public Immunogen Range | 1-337aa |
Calculated MW | 42kDa |
Observed MW | 40kDa |
Purification Method | Affinity purification |
Storage Buffer | PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Unit | bottle |
Specification | 50ul 100ul |
Reactivity | Human |
Application | WB |
Remark:These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder:Quick spin before use. If you have any questions, please contact us.
Note:
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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