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My CartReactivity：Mouse,Human;Mouse;Rat,Human,Rat
Application： IHC
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Host：Rabbit
Qty：
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| Name | Anti-DUSP8 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | IHC 1:50-200. |
| Target | DUSP8 |
| Background | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK，SAPK/JNK，p38)，which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases，different tissue distribution and subcellular localization，and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38，is expressed predominantly in the adult brain，heart，and skeletal muscle，is localized in the cytoplasm，and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. |
| Swiss Prot | Q13202 |
| Gene ID | 1850 |
| Subcellular Location | Cytoplasm Nucleus |
| Immunogen | A synthetic peptide of human DUSP8 |
| Public Immunogen Range | 1-51/625aa |
| Calculated MW | 66kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | bottle |
| Specification | 50ul 100ul |
| Reactivity | Human;Mouse;Rat Rat Mouse Human |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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