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My CartReactivity：Human,Mouse,Rat,Human;Mouse;Rat
Application： IHC
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Host：Rabbit
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| Name | Anti-GCLC Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Dilution Ratio | IHC 1:50-200. |
| Target | GCLC |
| Background | Glutamate-cysteine ligase，also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits，a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit，while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction. |
| Swiss Prot | P48506 |
| Gene ID | 2729 |
| Subcellular Location | Cytoplasm |
| Immunogen | A synthetic peptide of human GCLC |
| Public Immunogen Range | 50-100/637aa |
| Calculated MW | 73kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | bottle |
| Specification | 50ul 100ul |
| Reactivity | Human;Mouse;Rat Rat Mouse Human |
| Application | IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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