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My CartReactivity：Human,Human;Mouse;Rat,Mouse,Rat
Application： WB
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Host：Rabbit
Qty：
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| Name | Anti-CXCR2 Polyclonal Antibody |
| Host | Rabbit |
| Clone Type | Polyclonal Antibody |
| Subtype | IgG |
| Predicted Reactivity | Chimpanzee;Monkey |
| Dilution Ratio | WB 1:1000-3000. |
| Target | CXCR2 |
| Background | The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity，and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA)，a protein with melanoma growth stimulating activity，and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene，IL8RA，a gene encoding another high affinity IL8 receptor，as well as IL8RBP，a pseudogene of IL8RB，form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants，encoding the same protein，have been identified. |
| Swiss Prot | P25025 |
| Gene ID | 3579 |
| Subcellular Location | Cell membrane |
| Immunogen | A synthetic peptide of human CXCR2 |
| Public Immunogen Range | 1-51/360aa |
| Calculated MW | 41kDa |
| Observed MW | 47kDa |
| Purification Method | Affinity purification |
| Storage Buffer | PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | bottle |
| Specification | 50ul 100ul |
| Reactivity | Human;Mouse;Rat Rat Mouse Human |
| Application | WB |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Kindly reminder：Quick spin before use. If you have any questions, please contact us.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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