Freund's Adjuvant Incomplete
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Cat.No：F5506 Merck
Storage：2-8℃，1 year
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> Protein and Immunity > Other Reagents > Other Buffers/Reagents > Freund's Adjuvant Incomplete
Product Information
| Name | Freund's Adjuvant Incomplete |
| Storage | 2-8℃，1 year |
| Unit | bottle |
| Specification | 10ml |
产品简介：
弗氏完全佐剂是一种油包水的乳浊液，含结核分枝杆菌的细胞壁成分。佐剂活性来自于油滴中免疫原的持续释放，并刺激局部免疫反应。弗氏不完全佐剂用于初次免疫刺激。为了减少副作用，不含结核分枝杆菌成分的弗氏不完全佐剂用于加强免疫。
弗氏佐剂是现在动物实验中最常用的佐剂，分为不完全弗氏佐剂和完全弗氏佐剂。不完全弗氏佐剂是液体石蜡与羊毛脂混合而成，组分比为1～5：1，可根据需要而定，通常为2：1。不完全佐剂中加卡介苗(最终浓度为2～20mg/ml)或死的结核分枝杆菌，即为完全弗氏佐剂（FCA）。
相关介绍：
佐剂：一种能增强抗原免疫原性的试剂，又分为不完全佐剂和完全佐剂。
免疫佐剂能非特异性的加强或者修饰与其共同注入体内的抗原的免疫应答，因此与单独使用抗原相比，其抗体产量更大。其放大效应包括：一种免疫原的仓库，使其能在较长时间内缓慢释放从而向免疫系统提呈；免疫刺激被优化，几种一般免疫刺激剂和抗原于同一微环境中，并同时与抗原提呈相比和淋巴细胞相互作用；免疫系统相比非特异性活化，而这种活化对产生抗体的反应有益。
弗氏佐剂
是现在动物实验中常用的佐剂，分为不完全弗氏佐剂和完全弗氏佐剂。弗氏佐剂具有一定的毒性，在使用的时候一定注意用量。弗氏佐剂在使用的时候，先将弗氏佐剂与抗原按一定比例混合，佐剂和抗原体积比一般为1：1，制备成 "油包水"乳状液。混合的方式有研磨、注射器混合和超声。
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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