γ-Neuropeptide (rabbit)
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Cat.No：CLP1848 Solarbio
CAS：114882-65-4
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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Inhibitors & Antagonists & Agonists
PI3K/Akt/mTOR
Endocrinology & Hormones
Protein Tyrosine Kinase/PTK
Angiogenesis
HIF
Immunology & Inflammation
Stem Cells
Apoptosis
Metabolic Enzyme & Protease
Autophagy
ER Stress
Cell Cycle
Cytoskeleton
DNA Damage & DNA Repai
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Ubiquitin
JAK/STAT
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TGF-β/Smad
Hippo
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Pipette & Dispenser & Pipette Dispensing Instrument
Oscillating Mixing & Stirring & Dispersing Instrument
Temperature Control & Sampling & Grinding Crushing Instrument
Sterilization & Filtration Instruments
PCR Instrument & Light Glue Instrument
Spectrophotometer
Centrifuge
Shaker
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Product Information
| Product Type | Peptides |
| CAS | 114882-65-4 |
| Sequence(1LC) | DAGHGQISHKRHKTDSFVGLM-NH2 |
| Sequence(3LC) | Asp-Ala-Gly-His-Gly-Gln-Ile-Ser-His-Lys-Arg-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2 |
| Molecular Formula | C99H158N34O29S1 |
| Molecular Weight | 2320.59 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Neuropeptides & Related Peptides |
| Background | γ-Neuropeptide (rabbit) can be isolated from rabbit intestine. γ-Neuropeptide is an endogenous neurokinin peptide that acts as a neurokinin 2 (NK2) receptor agonist. γ-Neuropeptide mediates hypothalamic-pituitary-adrenal (HPA) axis， as well as reproductive hormone release. |
| In Vitro | γ-Neuropeptide induces stimulation of LH release by hemipituitaries from intact male rats into the medium. γ-Neuropeptide (1 nM-100 nM) has no effect on GH release from male rats anterior pituitaries. |
| In Vivo | γ-Neuropeptide (rabbit) (0.4-2.0 nmol/kg， intravenous injection) can lower blood pressure in rabbits. γ-Neoprotein (0.5-10 nmol， i.c.v) stimulates an increase in plasma LH in male rats. |
| Reference | [1]. Kage R， et al. Neuropeptide-gamma: a peptide isolated from rabbit intestine that is derived from gamma-preprotachykinin. J Neurochem. 1988 May;50(5):1412-7. [2]. Yuan L， et al. Characterization of tachykinin receptors mediating bronchomotor and vasodepressor responses to neuropeptide gamma and substance P in the anaesthetized rabbit. Pulm Pharmacol Ther. 1998 Feb;11(1):31-9. [3]. Debeljuk L， et al. Modulation of the hypothalamo-pituitary-gonadal axis and the pineal gland by neurokinin A， neuropeptide K and neuropeptide gamma. Peptides. 1999;20(2):285-99. [4]. Kalra PS， et al. Diverse effects of tachykinins on luteinizing hormone release in male rats: mechanism of action. Endocrinology. 1992 Sep;131(3):1195-201. [5]. Debeljuk L， et al. In vivo and in vitro effects of neuropeptide K and neuropeptide gamma on the release of growth hormone. Neuroreport. 1995 Dec 15;6(18):2457-60. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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