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My Cart> Peptides > Neuropeptides & Related Peptides > Crustacean cardioactive peptide，free acidCAS：309247-84-5
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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| Product Type | Peptides |
| CAS | 309247-84-5 |
| Sequence(1LC) | PFCNAFTGC |
| Sequence(3LC) | Pro-Phe-Cys-Asn-Ala-Phe-Thr-Gly-Cys |
| Molecular Formula | C42H58N10O12S2 |
| Molecular Weight | 959.1 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Neuropeptides & Related Peptides |
| Background | Crustacean cardioactive peptide，free acid is a highly conserved， amidated cyclic nonapeptide， first isolated from the pericardial organs of the shore crab Carcinus maenas， where it has a role in regulating heartbeat; Crustacean cardioactive peptide，free acid also modulates the neuronal activity in other arthropods. |
| In Vitro | Ultrabithorax and Abdominal-A are not necessary for specification of the CCAP-interneurons， but are absolutely required to prevent the death by apoptosis of the CCAP-efferent neurons. |
| In Vivo | CCAP， FMRFamide and SALDKNFMRFamide increase the mosquito antennal accessory pulsatile organ (APO) and heart contraction rates， increase hemolymph flow velocity in the antennal space. |
| Reference | [1]. Suggs JM， et al. CCAP and FMRFamide-like peptides accelerate the contraction rate of the antennal accessory pulsatile organs (auxiliary hearts) of mosquitoes. J Exp Biol. 2016 Aug 1;219(Pt 15):2388-95. [2]. Moris-Sanz M， et al. The study of the Bithorax-complex genes in patterning CCAP neurons reveals a temporal control of neuronal differentiation by Abd-B. Biol Open. 2015 Aug 14;4(9):1132-42. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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